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Cell Signal Transduction Research Antibodies
DLC-1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight122827 Da
Protein NameRho GTPase-activating protein 7
Human Gene Id10395
Human Swiss Prot NoQ96QB1
Mouse Gene Id50768
Mouse Swiss Prot NoQ9R0Z9
Rat Swiss Prot NoQ63744
SpecificityDLC-1 Polyclonal Antibody detects endogenous levels of DLC-1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDLC1; ARHGAP7; KIAA1723; STARD12; Rho GTPase-activating protein 7; Deleted in liver cancer 1 protein; DLC-1; HP protein; Rho-type GTPase-activating protein 7; START domain-containing protein 12; StARD12; StAR-related lipid transfer protein
Functionfunction:Functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.,sequence caution:Chimera. Sequence from position 1 to 13 is due to a chimera.,similarity:Contains 1 Rho-GAP domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 1 START domain.,tissue specificity:Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.,
Subcellular Locationnucleus,cytoplasm,cytosol,caveola,focal adhesion,cortical actin cytoskeleton,ruffle membrane,
ExpressionBrain,Heart,Lung,Trachea,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human RHG07. AA range:61-110
Gene NameDLC1
DilutionImmunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
BackgroundDLC1 Rho GTPase activating protein(DLC1) Homo sapiens This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010],
Conjugated Antibody
This product is also available conjugated. Format: E20-71356-Conjugate. Price: $485 / Size: 100μl.
E20-71356-FITC$485 / 100μlE20-71356-Biotin$485 / 100μlE20-71356-HRP$485 / 100μlE20-71356-AP$485 / 100μlE20-71356-AF350$485 / 100μlE20-71356-AF405M$485 / 100μlE20-71356-AF488$485 / 100μlE20-71356-AF514$485 / 100μlE20-71356-AF532$485 / 100μlE20-71356-AF555$485 / 100μlE20-71356-AF568$485 / 100μlE20-71356-AF405S$485 / 100μlE20-71356-AF405L$485 / 100μlE20-71356-AF546$485 / 100μlE20-71356-AF594$485 / 100μlE20-71356-AF610$485 / 100μlE20-71356-AF635$485 / 100μlE20-71356-AF647$485 / 100μlE20-71356-AF680$485 / 100μlE20-71356-AF700$485 / 100μlE20-71356-AF750$485 / 100μlE20-71356-AF790$485 / 100μlE20-71356-APC$485 / 100μlE20-71356-PE$485 / 100μlE20-71356-Cy3$485 / 100μlE20-71356-Cy5$485 / 100μlE20-71356-Cy5.5$485 / 100μlE20-71356-Cy7$485 / 100μlE20-71356-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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