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DHODH Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71345
  • Amount:

    100ul
  • Reactivity:

    Human,Mouse,Rat
  • Purification:

    . The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human DHODH. AA range:211-260
  • Source:

    Polyclonal, Rabbit
  • Western Blot analysis of Jurkat cells using DHODH Polyclonal Antibody
  • Gene Name:

    DHODH
  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
  • Protein Name:

    Dihydroorotate dehydrogenase
  • Human Gene Id:

    1723
  • Human Swiss Prot No:

    Q02127
  • Specificity:

    DHODH Polyclonal Antibody detects endogenous levels of DHODH protein.
  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Concentration:

    1 mg/ml
  • Storage Stability:

    -20°C/1 year
  • Other Name:

    DHODH; Dihydroorotate dehydrogenase; quinone); mitochondrial; DHOdehase; Dihydroorotate oxidaseMolecularWeight: 42867Da
  • Observed Band(KD):

    48
  • Background:

    dihydroorotate dehydrogenase (quinone)(DHODH) Homo sapiens The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008],
  • Function:

    catalytic activity:(S)-dihydroorotate + O(2) = orotate + H(2)O(2).,cofactor:Binds 1 FAD per subunit.,pathway:Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 4/6.,similarity:Belongs to the dihydroorotate dehydrogenase family.,
  • Subcellular Location:

    nucleoplasm,cytoplasm,mitochondrion,mitochondrial inner membrane,integral component of membrane,neuronal cell body,
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using DHODH Antibody. The picture on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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