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DHHC-15 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71342Amount:
100ulMolecular Weight:
39331DaReactivity:
Human,Mouse,RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human ZDHHC15. AA range:288-337Source:
Polyclonal, Rabbit
- Western Blot analysis of Jurkat cells using DHHC-15 Polyclonal Antibody
Gene Name:
ZDHHC15Dilution:
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.Protein Name:
Palmitoyltransferase ZDHHC15Human Gene Id:
158866Human Swiss Prot No:
Q96MV8Specificity:
DHHC-15 Polyclonal Antibody detects endogenous levels of DHHC-15 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
ZDHHC15; Palmitoyltransferase ZDHHC15; Zinc finger DHHC domain-containing protein 15; DHHC-15Observed Band(KD):
38Background:
zinc finger DHHC-type containing 15(ZDHHC15) Homo sapiens The protein encoded by this gene belongs to the DHHC palmitoyltransferase family. Mutations in this gene are associated with mental retardatio X-linked type 91 (MRX91). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],Function:
catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,disease:Defects in ZDHHC15 are the cause of mental retardation X-linked type 91 (MRX91) [MIM:300577]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.,domain:The DHHC domain is required for palmitoyltransferase activity.,function:Palmitoyltransferase specific for GAP43 and DLG4/PSD95.,PTM:Autopalmitoylated.,similarity:Belongs to the DHHC palmitoyltransferase family.,similarity:Contains 1 DHHC-type zinc finger.,tissue specificity:Expressed in placenta, liver, lung, kidney, heart and brain.,Subcellular Location:
Golgi apparatus,integral component of membrane,extracellular exosome,
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