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DGK-κ Polyclonal Antibody
Datasheet
Catalog Number:
E20-71339Amount:
100ugSwiss-Prot No.:
Q5KSL6Molecular Weight:
141829Price:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human DGKK. AA range:1221-1270Specificity/Sensitivity:
DGK-κ Polyclonal Antibody detects endogenous levels of DGK-κ protein.Other Names:
DGKK; Diacylglycerol kinase kappa; DAG kinase kappa; 142 kDa diacylglycerol kinase; Diglyceride kinase kappa; DGK-kappaStorage/Stability:
-20°C/1 yearSource:
RabbitProtein Concentration:
1 mg/mlGene Name:
RDGKKDilution:
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.Background:
diacylglycerol kinase kappa(DGKK) Homo sapiens The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011].Gene ID:
139189UniPort summary Function:
catalytic activity:ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.,enzyme regulation:Inhibited in response to H(2)O(2).,function:Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).,PTM:Phosphorylated at Tyr-78 by some member of the SRC family in response to H(2)O(2).,similarity:Belongs to the eukaryotic diacylglycerol kinase family.,similarity:Contains 1 DAGKc domain.,similarity:Contains 1 PH domain.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,subunit:Does not form homooligomers.,tissue specificity:Expressed in testis, and to a lesser extent in placenta.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Immunofluorescence analysis of COS7 cells using DGKK Antibody. The picture on the right is blocked with the synthesized peptide. on
Immunohistochemistry analysis of paraffin-embedded human brain tissue using DGKK Antibody. The picture the right is blocked with the synthesized peptide.
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