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DCAMKL2 Polyclonal Antibody

Human;Mouse
WB;IF/ICC;ELISA
Polyclonal, Rabbit,IgG
Price on request
Quantity

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Gene NameDCLK2

Product Information

Protein NameSerine/threonine-protein kinase DCLK2
Human Gene Id166614
Human Swiss Prot NoQ8N568
Mouse Gene Id70762
Mouse Swiss Prot NoQ6PGN3
SpecificityDCAMKL2 Polyclonal Antibody detects endogenous levels of DCAMKL2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDCLK2; DCAMKL2; DCDC3B; DCK2; Serine/threonine-protein kinase DCLK2; CaMK-like CREB regulatory kinase 2; CL2; CLICK-II; CLICK2; Doublecortin domain-containing protein 3B; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2
Molecular Weight83612Da
Observed Band(KD)83
Functioncatalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 doublecortin domains.,
Subcellular LocationCytoplasm, cytoskeleton. Colocalizes with microtubules. .
ExpressionExpressed in the brain, heart and eyes.
ImmunogenThe antiserum was produced against synthesized peptide derived from human DCLK2. AA range:1-50
DilutionWestern Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
BackgroundThis gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alterna
Western blot analysis of lysates from HepG2 cells, using DCLK2 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HepG2 cells, using DCLK2 Antibody. The lane on the right is blocked with the synthesized peptide.
Western Blot analysis of various cells using DCAMKL2 Polyclonal Antibody.
Western Blot analysis of various cells using DCAMKL2 Polyclonal Antibody.

Conjugated Antibody

This product is also available conjugated. Format: E20-712998-Conjugate. Price: $485 / Size: 100μl.

E20-712998-FITC$485 / 100μlE20-712998-Biotin$485 / 100μlE20-712998-HRP$485 / 100μlE20-712998-AP$485 / 100μlE20-712998-AF350$485 / 100μlE20-712998-AF405M$485 / 100μlE20-712998-AF488$485 / 100μlE20-712998-AF514$485 / 100μlE20-712998-AF532$485 / 100μlE20-712998-AF555$485 / 100μlE20-712998-AF568$485 / 100μlE20-712998-AF405S$485 / 100μlE20-712998-AF405L$485 / 100μlE20-712998-AF546$485 / 100μlE20-712998-AF594$485 / 100μlE20-712998-AF610$485 / 100μlE20-712998-AF635$485 / 100μlE20-712998-AF647$485 / 100μlE20-712998-AF680$485 / 100μlE20-712998-AF700$485 / 100μlE20-712998-AF750$485 / 100μlE20-712998-AF790$485 / 100μlE20-712998-APC$485 / 100μlE20-712998-PE$485 / 100μlE20-712998-Cy3$485 / 100μlE20-712998-Cy5$485 / 100μlE20-712998-Cy5.5$485 / 100μlE20-712998-Cy7$485 / 100μlE20-712998-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.