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D1DR Polyclonal Antibody
Datasheet
Catalog Number:
E20-71277Amount:
100ulMolecular Weight:
49293DaPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human DRD1. AA range:135-184Source:
Polyclonal, Rabbit
- Western Blot analysis of HepG2 cells using D1DR Polyclonal Antibody
Gene Name:
DRD1Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.Protein Name:
D(1A) dopamine receptor Human Gene Id:1812Human Swiss Prot No:
P21728Specificity:
D1DR Polyclonal Antibody detects endogenous levels of D1DR protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
DRD1; D(1A) dopamine receptor; Dopamine D1 receptorObserved Band(KD):
50Background:
dopamine receptor D1(DRD1) Homo sapiens This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008],Function:
function:This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,subcellular location:Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14.,subunit:Interacts with DNAJC14 via its C-terminus (By similarity). Interacts with DRD1IP.,tissue specificity:Detected in caudate, nucleus accumbens and in the olfactory tubercle.,Subcellular Location:
nucleus,endoplasmic reticulum membrane,plasma membrane,integral component of plasma membrane,nonmotile primary cilium,ciliary membrane,Expression:
Brain,
- Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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Catalog Number
- Amount:100ul
- Price:225$
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