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Cytochrome c1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71258Amount:
100ulMolecular Weight:
35390DaApplications:
WB; IF/ICC;ELISAReactivity:
Human;MousePurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human CYC1. AA range:132-181Source:
Polyclonal, Rabbit,IgG
- Chen, Puxiang, et al. "Long noncoding RNA LINC00152 promotes cell proliferation through competitively binding endogenous miR‐125b with MCL‐1 by regulating mitochondrial apoptosis pathways in ovarian cancer." Cancer medicine 7.9 (2018): 4530-4541.
Gene Name:
CYC1Dilution:
WB 1:500-2000; IF/ICC 1:100-500;ELISA 1:5000-20000Protein Name:
Cytochrome c1 heme protein mitochondrialHuman Gene Id:
1537Human Swiss Prot No:
P08574Mouse Gene Id:
66445Mouse Swiss Prot No:
Q9D0M3Specificity:
Cytochrome c1 Polyclonal Antibody detects endogenous levels of Cytochrome c1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
CYC1; Cytochrome c1; heme protein, mitochondrial; Complex III subunit 4; Complex III subunit IV; Cytochrome b-c1 complex subunit 4; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit; Cytochrome c-1Observed Band(KD):
35Background:
This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6. [provided by RefSeq, Dec 2013],Function:
function:This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.,PTM:Binds 1 heme group per subunit.,similarity:Belongs to the cytochrome c family.,subunit:The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).,Subcellular Location:
Mitochondrion inner membrane ; Single-pass membrane protein .Expression:
Brain,Kidney,Lung,Skin,
- Western Blot analysis of various cells using Cytochrome c1 Polyclonal Antibody diluted at 1:500
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