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Cell Signal Transduction Research Antibodies

Cystatin 8 Polyclonal Antibody

E20-71248Cite ID: EN0051381DatasheetCOAMSDS
Human;Mouse
IHC-p;IF(paraffin section);ELISA
Polyclonal, Rabbit,IgG
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight16275Da
Protein NameCystatin-8
Human Gene Id10047
Human Swiss Prot NoO60676
Mouse Gene Id13012
Mouse Swiss Prot NoP32766
SpecificityCystatin 8 Polyclonal Antibody detects endogenous levels of Cystatin 8 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCST8; CRES; Cystatin-8; Cystatin-related epididymal spermatogenic protein
Functionfunction:Performs a specialized role during sperm development and maturation.,similarity:Belongs to the cystatin family.,tissue specificity:Proximal caput region of the epididymis. Lower expression in the testis. Within the testis it is localized to the elongating spermatids, whereas within the epididymis it is exclusively synthesized by the proximal caput epithelium.,
Subcellular LocationSecreted.
ExpressionProximal caput region of the epididymis. Lower expression in the testis. Within the testis it is localized to the elongating spermatids, whereas within the epididymis it is exclusively synthesized by the proximal caput epithelium.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CST8. AA range:31-80
Gene NameCST8
DilutionImmunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
BackgroundThe cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein similar to type 2 cystatins. The encoded protein exhibits highly tissue-specific expression in the reproductive tract, suggesting implicit roles in reproduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],

Conjugated Antibody

This product is also available conjugated. Format: E20-71248-Conjugate. Price: $485 / Size: 100μl.

E20-71248-FITC$485 / 100μlE20-71248-Biotin$485 / 100μlE20-71248-HRP$485 / 100μlE20-71248-AP$485 / 100μlE20-71248-AF350$485 / 100μlE20-71248-AF405M$485 / 100μlE20-71248-AF488$485 / 100μlE20-71248-AF514$485 / 100μlE20-71248-AF532$485 / 100μlE20-71248-AF555$485 / 100μlE20-71248-AF568$485 / 100μlE20-71248-AF405S$485 / 100μlE20-71248-AF405L$485 / 100μlE20-71248-AF546$485 / 100μlE20-71248-AF594$485 / 100μlE20-71248-AF610$485 / 100μlE20-71248-AF635$485 / 100μlE20-71248-AF647$485 / 100μlE20-71248-AF680$485 / 100μlE20-71248-AF700$485 / 100μlE20-71248-AF750$485 / 100μlE20-71248-AF790$485 / 100μlE20-71248-APC$485 / 100μlE20-71248-PE$485 / 100μlE20-71248-Cy3$485 / 100μlE20-71248-Cy5$485 / 100μlE20-71248-Cy5.5$485 / 100μlE20-71248-Cy7$485 / 100μlE20-71248-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.