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CYP2U1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71224Amount:
100ulMolecular Weight:
61987 DaObserved Band:61Applications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2U1. AA range:281-330Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using CYP2U1 Polyclonal Antibody
Gene Name:
CYP2U1Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
Cytochrome P450 2U1Human Gene Id:
113612Human Swiss Prot No:
Q7Z449Mouse Gene Id:
71519Mouse Swiss Prot No:
Q9CX98Rat Gene Id:
310848Rat Swiss Prot No:
Q4V8D1Specificity:
CYP2U1 Polyclonal Antibody detects endogenous levels of CYP2U1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
CYP2U1; Cytochrome P450 2U1Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008],Function:
catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,developmental stage:Expressed in fetal thymus.,function:Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Widely expressed with stronger expression in thymus, heart and cerebellum.,Subcellular Location:
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein . Mitochondrion inner membrane ; Multi-pass membrane protein .Expression:
Widely expressed with stronger expression in thymus, heart and cerebellum.
- Western blot analysis of lysates from HeLa and Lovo cells, using Cytochrome P450 2U1 Antibody. The lane on the right is blocked with the synthesized peptide.
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