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Med18 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71185Amount:
100ulMolecular Weight:
22040 DaObserved Band:22 KDApplications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human PPIF. AA range:86-135Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using Cyclophilin F Polyclonal Antibody diluted at 1:2000
Gene Name:
PPIFDilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
Peptidyl-prolyl cis-trans isomerase F mitochondrialHuman Gene Id:
10105Human Swiss Prot No:
P30405Mouse Gene Id:
105675Mouse Swiss Prot No:
Q99KR7Rat Gene Id:
282819Rat Swiss Prot No:
P29117Specificity:
Cyclophilin F Polyclonal Antibody detects endogenous levels of Cyclophilin F protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
PPIF; CYP3; Peptidyl-prolyl cis-trans isomerase F; mitochondrial; PPIase F; Cyclophilin F; Rotamase FBackground:
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008],Function:
catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain.,Subcellular Location:
Mitochondrion matrix .Expression:
Blood,Cord blood,Ovary,
- Western Blot analysis of HuvEc cells using Cyclophilin F Polyclonal Antibody diluted at 1:2000
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