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CTDSP1 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71150

  • Amount:

    100ul

  • Molecular Weight:

    29203 DaObserved Band:30 KD

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CTDSP1. AA range:1-50

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using CTDSP1 Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

  • Gene Name:

    CTDSP1

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

  • Protein Name:

    Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

  • Human Gene Id:

    58190

  • Human Swiss Prot No:

    Q9GZU7

  • Mouse Gene Id:

    227292

  • Mouse Swiss Prot No:

    P58466

  • Specificity:

    CTDSP1 Polyclonal Antibody detects endogenous levels of CTDSP1 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CTDSP1; NIF3; NLIIF; SCP1; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; Nuclear LIM interactor-interacting factor 3; NLI-IF; NLI-interacting factor 3; Small C-terminal domain phosphatase 1; SCP1; Small CTD ph

  • Background:

    CTD small phosphatase 1(CTDSP1) Homo sapiens This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],

  • Function:

    catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,similarity:Contains 1 FCP1 homology domain.,subunit:May interact with LDB1 .,tissue specificity:Ubiquitously expressed, with highest expression in spleen, lung and placenta.,

  • Subcellular Location:

    Nucleus . Colocalizes with RNA polymerase II.

  • Expression:

    Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.

  • Western blot analysis of mouse-brain HELA KB SH-SY5Y 293T 3T3 lysis using CTDSP1 antibody. Antibody was diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

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