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CstF-64 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71145
  • Amount:

    100ul
  • Molecular Weight:

    60959 DaObserved Band:60 KD
  • Applications:

    WB;IHC-p;IF/ICC;ELISA
  • Reactivity:

    Human;Mouse
  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CSTF2. AA range:11-60
  • Source:

    Polyclonal, Rabbit,IgG
  • Western Blot analysis of various cells using CstF-64 Polyclonal Antibody diluted at 1:1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
  • Gene Name:

    CSTF2
  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
  • Protein Name:

    Cleavage stimulation factor subunit 2
  • Human Gene Id:

    1478
  • Human Swiss Prot No:

    P33240
  • Mouse Gene Id:

    108062
  • Mouse Swiss Prot No:

    Q8BIQ5
  • Specificity:

    CstF-64 Polyclonal Antibody detects endogenous levels of CstF-64 protein.
  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Concentration:

    1 mg/ml
  • Storage Stability:

    -20°C/1 year
  • Other Name:

    CSTF2; Cleavage stimulation factor subunit 2; CF-1 64 kDa subunit; Cleavage stimulation factor 64 kDa subunit; CSTF 64 kDa subunit; CstF-64
  • Background:

    This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008],
  • Function:

    function:One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs.,induction:Up-regulated during the G0 to S phase transition.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:The CSTF complex is composed of CSTF1 (50 kDa subunit), CSTF2 (64 kDa subunit) and CSTF3 (77 kDa subunit). CSTF2 directly interacts with CSTF3, SYMPK and RPO2TC1. Interacts with HSF1 in heat-stressed cells. Interacts with FIP1L1.,
  • Subcellular Location:

    Nucleus . Localized with DDX1 in cleavage bodies.
  • Expression:

    Kidney,Ovary,
  • Immunofluorescence analysis of HeLa cells, using CSTF2 Antibody. The picture on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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CstF-64 Polyclonal Antibody | EnoGene Biotech Co. Ltd