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CSP Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71135

  • Amount:

    100ul

  • Molecular Weight:

    22149 DaObserved Band:30 KD

  • Applications:

    WB;ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human DNAJC5. AA range:131-180

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using CSP Polyclonal Antibody diluted at 1:2000

  • Gene Name:

    DNAJC5

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    DnaJ homolog subfamily C member 5

  • Human Gene Id:

    80331

  • Human Swiss Prot No:

    Q9H3Z4

  • Mouse Gene Id:

    13002

  • Mouse Swiss Prot No:

    P60904

  • Rat Gene Id:

    79130

  • Rat Swiss Prot No:

    P60905

  • Specificity:

    CSP Polyclonal Antibody detects endogenous levels of CSP protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    DNAJC5; CSP; DnaJ homolog subfamily C member 5; Cysteine string protein; CSP

  • Background:

    This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010],

  • Function:

    function:May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings.,PTM:Fatty acylated. Heavily palmitoylated in the cysteine string motif.,similarity:Contains 1 J domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,tissue specificity:Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.,

  • Subcellular Location:

    Cytoplasm, cytosol . Membrane ; Lipid-anchor . Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane . Melanosome . Cell membrane . The association with membranes is regulated by palmitoylation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). .

  • Expression:

    Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.

  • Western blot analysis of the lysates from HeLa cells using DNAJC5 antibody.

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Catalog Number

  • Amount:100ul
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CSP Polyclonal Antibody | EnoGene Biotech Co. Ltd