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Csk Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71131

  • Amount:

    100ul

  • Molecular Weight:

    50704 DaObserved Band:50 KD

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CSK. AA range:330-379

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using Csk Polyclonal Antibody diluted at 1:1000

  • Gene Name:

    CSK

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

  • Protein Name:

    Tyrosine-protein kinase CSK

  • Human Gene Id:

    1445

  • Human Swiss Prot No:

    P41240

  • Mouse Gene Id:

    12988

  • Mouse Swiss Prot No:

    P41241

  • Rat Gene Id:

    315707

  • Rat Swiss Prot No:

    P32577

  • Specificity:

    Csk Polyclonal Antibody detects endogenous levels of Csk protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CSK; Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL

  • Background:

    catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:Mainly cytoplasmic, also present in lipid rafts.,subunit:Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1.,tissue specificity:Expressed in lung and macrophages.,

  • Function:

    catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:Mainly cytoplasmic, also present in lipid rafts.,subunit:Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1.,tissue specificity:Expressed in lung and macrophages.,

  • Subcellular Location:

    Cytoplasm . Cell membrane . Mainly cytoplasmic, also present in lipid rafts. .

  • Expression:

    Expressed in lung and macrophages.

  • Western Blot analysis of 22RV1 cells using Csk Polyclonal Antibody diluted at 1:1000

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Catalog Number

  • Amount:100ul
  • Price:225$

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Csk Polyclonal Antibody | EnoGene Biotech Co. Ltd