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CsGalNAcT-2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-71129Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human CSGALNACT2. AA range:61-110Source:
Polyclonal, RabbitGene Name:
CSGALNACT2Dilution:
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
- Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CSGALNACT2 Antibody. The picture on the right is blocked with the synthesized peptide.
Background:
chondroitin sulfate N-acetylgalactosaminyltransferase 2(CSGALNACT2) Homo sapiens This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome X. [provided by RefSeq, Feb 2016],Protein Name:
Chondroitin sulfate N-acetylgalactosaminyltransferase 2Human Gene Id:
55454Human Swiss Prot No:
Q8N6G5Mouse Gene Id:
78752Mouse Swiss Prot No:
Q8C1F4Specificity:
CsGalNAcT-2 Polyclonal Antibody detects endogenous levels of CsGalNAcT-2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
CSGALNACT2; CHGN2; GALNACT2; Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Chondroitin beta-1; 4-N-acetylgalactosaminyltransferase 2; Beta4GalNAcT-2; GalNAcT-2MolecularWeight(Da):
62572Observed Band(KD):
63Function:
catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronyl-(1->3)-D-galactosyl-proteoglycan = UDP + N-acetyl-D-galactosaminyl-(1->4)-beta-D-glucuronyl-(1->3)-beta-D-galactosylproteoglycan.,function:Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains.,online information:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2,online information:GlycoGene database,similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family.,tissue specificity:Ubiquitous.,Subcellular Location:
Golgi membrane,membrane,integral component of membrane,integral component of Golgi membrane,Golgi cisterna membrane,Expression:
Endothelial cell,Fetal liver,Lung,Pancreas,
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