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CROT Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71118

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    Synthesized peptide derived from CROT . at AA range: 190-270

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    CROT

  • Dilution:

    Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

  • Background:

    carnitine O-octanoyltransferase(CROT) Homo sapiens This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009],

  • Protein Name:

    Peroxisomal carnitine O-octanoyltransferase

  • Human Gene Id:

    54677

  • Human Swiss Prot No:

    Q9UKG9

  • Mouse Gene Id:

    74114

  • Mouse Swiss Prot No:

    Q9DC50

  • Rat Gene Id:

    83842

  • Rat Swiss Prot No:

    P11466

  • Specificity:

    CROT Polyclonal Antibody detects endogenous levels of CROT protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CROT; COT; Peroxisomal carnitine O-octanoyltransferase; COT

  • MolecularWeight(Da):

    70178

  • Observed Band(KD):

    72

  • Function:

    catalytic activity:Octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine.,function:Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl-CoA, to its corresponding carnitine ester.,pathway:Lipid metabolism; fatty acid beta-oxidation.,similarity:Belongs to the carnitine/choline acetyltransferase family.,subunit:Monomer.,

  • Subcellular Location:

    mitochondrion,peroxisome,peroxisomal matrix,intracellular membrane-bounded organelle,

  • Expression:

    B-cell,Colon,Skin,

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Catalog Number

  • Amount:100ul
  • Price:225$

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