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Cell Signal Transduction Research Antibodies
CRMP-3 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight61878 Da
Protein NameDihydropyrimidinase-related protein 4
Human Gene Id10570
Human Swiss Prot NoO14531
Mouse Swiss Prot NoO35098
Rat Gene Id25417
Rat Swiss Prot NoQ62951
SpecificityCRMP-3 Polyclonal Antibody detects endogenous levels of CRMP-3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameDPYSL4; CRMP3; ULIP4; Dihydropyrimidinase-related protein 4; DRP-4; Collapsin response mediator protein 3; CRMP-3; UNC33-like phosphoprotein 4; ULIP-4
Observed Band(KD)62
Functiondisease:Antibodies against post-translationally modified DPYSL4, also called anti-CV2 autoantibodies, are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct result of the tumor mass or metastasis, but attributed to remote effects of the cancer.,function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1.,
Subcellular Locationcytoplasm,cytosol,
ExpressionBrain,Fetal brain,Retina,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human DPYSL4. AA range:91-140
Gene NameDPYSL4
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgrounddisease:Antibodies against post-translationally modified DPYSL4, also called anti-CV2 autoantibodies, are present in sera from patients with paraneoplastic neurological diseases (PND). PND are disorders of the nervous system associated with various systemic cancers which are not a direct result of the tumor mass or metastasis, but attributed to remote effects of the cancer.,function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1.,
Conjugated Antibody
This product is also available conjugated. Format: E20-71117-Conjugate. Price: $485 / Size: 100μl.
E20-71117-FITC$485 / 100μlE20-71117-Biotin$485 / 100μlE20-71117-HRP$485 / 100μlE20-71117-AP$485 / 100μlE20-71117-AF350$485 / 100μlE20-71117-AF405M$485 / 100μlE20-71117-AF488$485 / 100μlE20-71117-AF514$485 / 100μlE20-71117-AF532$485 / 100μlE20-71117-AF555$485 / 100μlE20-71117-AF568$485 / 100μlE20-71117-AF405S$485 / 100μlE20-71117-AF405L$485 / 100μlE20-71117-AF546$485 / 100μlE20-71117-AF594$485 / 100μlE20-71117-AF610$485 / 100μlE20-71117-AF635$485 / 100μlE20-71117-AF647$485 / 100μlE20-71117-AF680$485 / 100μlE20-71117-AF700$485 / 100μlE20-71117-AF750$485 / 100μlE20-71117-AF790$485 / 100μlE20-71117-APC$485 / 100μlE20-71117-PE$485 / 100μlE20-71117-Cy3$485 / 100μlE20-71117-Cy5$485 / 100μlE20-71117-Cy5.5$485 / 100μlE20-71117-Cy7$485 / 100μlE20-71117-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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