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COX6c Polyclonal Antibody
Datasheet
Catalog Number:
E20-71078Amount:
100ulMolecular Weight:
8781 DaObserved Band:32 KDApplications:
WB;IHC-p;IF/ICC;ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human COX6C. AA range:11-60Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using COX6c Polyclonal Antibody
Gene Name:
COX6CDilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.Protein Name:
Cytochrome c oxidase subunit 6CHuman Gene Id:
1345Human Swiss Prot No:
P09669Mouse Gene Id:
12864Mouse Swiss Prot No:
Q9CPQ1Specificity:
COX6c Polyclonal Antibody detects endogenous levels of COX6c protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
COX6C; Cytochrome c oxidase subunit 6C; Cytochrome c oxidase polypeptide VIcBackground:
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010],Function:
function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase subunit 6c family.,Subcellular Location:
Mitochondrion inner membrane ; Single-pass membrane protein .Expression:
Eye,
- Immunofluorescence analysis of HepG2 cells, using COX6C Antibody. The picture on the right is blocked with the synthesized peptide.
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