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COX4 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71074

  • Amount:

    100ul

  • Molecular Weight:

    19577 DaObserved Band:17 KD

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human COX41. AA range:11-60

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using COX4 Polyclonal Antibody

  • Gene Name:

    COX4I1

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

  • Protein Name:

    Cytochrome c oxidase subunit 4 isoform 1 mitochondrial

  • Human Gene Id:

    1327

  • Human Swiss Prot No:

    P13073

  • Mouse Swiss Prot No:

    P19783

  • Specificity:

    COX4 Polyclonal Antibody detects endogenous levels of COX4 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    COX4I1; COX4; Cytochrome c oxidase subunit 4 isoform 1; mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1

  • Background:

    Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes

  • Function:

    function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase IV family.,tissue specificity:Ubiquitous.,

  • Subcellular Location:

    Mitochondrion inner membrane ; Single-pass membrane protein .

  • Expression:

    Ubiquitous.

  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using COX41 Antibody. The picture on the right is blocked with the synthesized peptide.

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