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Cell Signal Transduction Research Antibodies
COX11 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight31430Da
Protein NameCytochrome c oxidase assembly protein COX11 mitochondrial
Human Gene Id1353
Human Swiss Prot NoQ9Y6N1
Mouse Gene Id69802
Mouse Swiss Prot NoQ6P8I6
SpecificityCOX11 Polyclonal Antibody detects endogenous levels of COX11 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCOX11; Cytochrome c oxidase assembly protein COX11; mitochondrial
Observed Band(KD)31
Functionfunction:Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.,similarity:Belongs to the COX11/ctaG family.,subunit:Interacts with CNNM4/ACDP4.,tissue specificity:Ubiquitous.,
Subcellular Locationmitochondrion,mitochondrial inner membrane,integral component of membrane,
ExpressionBrain,Cerebellum,Corpus callosum,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human COX11. AA range:51-100
Gene NameCOX11
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
BackgroundCOX11, cytochrome c oxidase copper chaperone(COX11) Homo sapiens Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to c
Conjugated Antibody
This product is also available conjugated. Format: E20-71069-Conjugate. Price: $485 / Size: 100μl.
E20-71069-FITC$485 / 100μlE20-71069-Biotin$485 / 100μlE20-71069-HRP$485 / 100μlE20-71069-AP$485 / 100μlE20-71069-AF350$485 / 100μlE20-71069-AF405M$485 / 100μlE20-71069-AF488$485 / 100μlE20-71069-AF514$485 / 100μlE20-71069-AF532$485 / 100μlE20-71069-AF555$485 / 100μlE20-71069-AF568$485 / 100μlE20-71069-AF405S$485 / 100μlE20-71069-AF405L$485 / 100μlE20-71069-AF546$485 / 100μlE20-71069-AF594$485 / 100μlE20-71069-AF610$485 / 100μlE20-71069-AF635$485 / 100μlE20-71069-AF647$485 / 100μlE20-71069-AF680$485 / 100μlE20-71069-AF700$485 / 100μlE20-71069-AF750$485 / 100μlE20-71069-AF790$485 / 100μlE20-71069-APC$485 / 100μlE20-71069-PE$485 / 100μlE20-71069-Cy3$485 / 100μlE20-71069-Cy5$485 / 100μlE20-71069-Cy5.5$485 / 100μlE20-71069-Cy7$485 / 100μlE20-71069-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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