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Connexin 25 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71041

  • Amount:

    100ul

  • Molecular Weight:

    25860Da

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human GJB7. AA range:21-70

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using Connexin 25 Polyclonal Antibody diluted at 1:500

  • Gene Name:

    GJB7

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

  • Protein Name:

    Gap junction beta-7 protein

  • Human Gene Id:

    375519

  • Human Swiss Prot No:

    Q6PEY0

  • Specificity:

    Connexin 25 Polyclonal Antibody detects endogenous levels of Connexin 25 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    GJB7; CX25; Gap junction beta-7 protein; Connexin-25; Cx25

  • Observed Band(KD):

    24

  • Background:

    Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008],

  • Function:

    function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Beta-type (group I) subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:Weakly expressed in placenta.,

  • Subcellular Location:

    Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .

  • Expression:

    Weakly expressed in placenta.Products Images

  • Western blot analysis of lysates from HT-29 cells, using GJB7 Antibody. The lane on the right is blocked with the synthesized peptide.

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