COL6A1 Polyclonal Antibody

Name: COL6A1 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-71034
Price: 225 USD
Availability: InStock

E20-71034Cite ID: EN0051167Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight108529Da

Protein NameCollagen alpha-1(VI) chain

Human Gene Id1291

Human Swiss Prot NoP12109

Mouse Gene Id12833

Mouse Swiss Prot NoQ04857

SpecificityCOL6A1 Polyclonal Antibody detects endogenous levels of COL6A1 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameCOL6A1; Collagen alpha-1(VI) chain

Functiondisease:Defects in COL6A1 are a cause of Bethlem myopathy (BM) [MIM:158810]. BM is a rare autosomal dominant proximal myopathy characterized by early childhood onset (complete penetrance by the age of 5) and joint contractures most frequently affecting the elbows and ankles.,function:Collagen VI acts as a cell-binding protein.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the type VI collagen family.,similarity:Contains 3 VWFA domains.,subunit:Trimers composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI).,

Subcellular Locationextracellular region,collagen trimer,collagen type VI trimer,lysosomal membrane,endoplasmic reticulum lumen,membrane,extracellular matrix,sarcolemma,protein complex,extracellular exosome,

ExpressionBlood,Brain,Fetal brain cortex,Fibroblast,Kidney,Liver,Ovary,Placenta,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human Collagen VI alpha1. AA range:191-240

Gene NameCOL6A1

DilutionImmunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Backgroundcollagen type VI alpha 1 chain(COL6A1) Homo sapiens The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-71034-Conjugate. Price: $485 / Size: 100μl.

E20-71034-FITC$485 / 100μlE20-71034-Biotin$485 / 100μlE20-71034-HRP$485 / 100μlE20-71034-AP$485 / 100μlE20-71034-AF350$485 / 100μlE20-71034-AF405M$485 / 100μlE20-71034-AF488$485 / 100μlE20-71034-AF514$485 / 100μlE20-71034-AF532$485 / 100μlE20-71034-AF555$485 / 100μlE20-71034-AF568$485 / 100μlE20-71034-AF405S$485 / 100μlE20-71034-AF405L$485 / 100μlE20-71034-AF546$485 / 100μlE20-71034-AF594$485 / 100μlE20-71034-AF610$485 / 100μlE20-71034-AF635$485 / 100μlE20-71034-AF647$485 / 100μlE20-71034-AF680$485 / 100μlE20-71034-AF700$485 / 100μlE20-71034-AF750$485 / 100μlE20-71034-AF790$485 / 100μlE20-71034-APC$485 / 100μlE20-71034-PE$485 / 100μlE20-71034-Cy3$485 / 100μlE20-71034-Cy5$485 / 100μlE20-71034-Cy5.5$485 / 100μlE20-71034-Cy7$485 / 100μlE20-71034-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.