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Cell Signal Transduction Research Antibodies
COL12A1 Polyclonal AntibodyAntibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight333147Da
Protein NameCollagen alpha-1(XII) chain
Human Gene Id1303
Human Swiss Prot NoQ99715
Mouse Swiss Prot NoQ60847
SpecificityCOL12A1 Polyclonal Antibody detects endogenous levels of COL12A1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCOL12A1; COL12A1L; Collagen alpha-1(XII) chain
Functionalternative products:The final tissue form of collagen XII may contain homotrimers of either isoform 1 or isoform 2 or any combination of isoform 1 and isoform 2,function:Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.,PTM:Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.,PTM:O-glycosylation of isoform 1; glycosaminoglycan of chondroitin-sulfate type.,PTM:The triple-helical tail is stabilized by disulfide bonds at each end.,similarity:Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:Contains 18 fibronectin type-III dom
Subcellular Locationextracellular region,collagen trimer,collagen type XII trimer,extracellular space,endoplasmic reticulum lumen,extracellular matrix,extracellular exosome,extracellular vesicle,
ExpressionCornea,Liver,Peripheral Nervous System,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human Collagen XII alpha1. AA range:1481-1530
Gene NameCOL12A1
DilutionImmunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundcollagen type XII alpha 1 chain(COL12A1) Homo sapiens This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-71010-Conjugate. Price: $485 / Size: 100μl.
E20-71010-FITC$485 / 100μlE20-71010-Biotin$485 / 100μlE20-71010-HRP$485 / 100μlE20-71010-AP$485 / 100μlE20-71010-AF350$485 / 100μlE20-71010-AF405M$485 / 100μlE20-71010-AF488$485 / 100μlE20-71010-AF514$485 / 100μlE20-71010-AF532$485 / 100μlE20-71010-AF555$485 / 100μlE20-71010-AF568$485 / 100μlE20-71010-AF405S$485 / 100μlE20-71010-AF405L$485 / 100μlE20-71010-AF546$485 / 100μlE20-71010-AF594$485 / 100μlE20-71010-AF610$485 / 100μlE20-71010-AF635$485 / 100μlE20-71010-AF647$485 / 100μlE20-71010-AF680$485 / 100μlE20-71010-AF700$485 / 100μlE20-71010-AF750$485 / 100μlE20-71010-AF790$485 / 100μlE20-71010-APC$485 / 100μlE20-71010-PE$485 / 100μlE20-71010-Cy3$485 / 100μlE20-71010-Cy5$485 / 100μlE20-71010-Cy5.5$485 / 100μlE20-71010-Cy7$485 / 100μlE20-71010-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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