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CNOT7 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-71002
  • Amount:

    100ul
  • Molecular Weight:

    32745Da
  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA
  • Reactivity:

    Human;Mouse
  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CNOT7. AA range:10-59
  • Source:

    Polyclonal, Rabbit,IgG
  • Western Blot analysis of various cells using CNOT7 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
  • Gene Name:

    CNOT7
  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
  • Protein Name:

    CCR4-NOT transcription complex subunit 7
  • Human Gene Id:

    29883
  • Human Swiss Prot No:

    Q9UIV1
  • Mouse Gene Id:

    18983
  • Mouse Swiss Prot No:

    Q60809
  • Specificity:

    CNOT7 Polyclonal Antibody detects endogenous levels of CNOT7 protein.
  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Concentration:

    1 mg/ml
  • Storage Stability:

    -20°C/1 year
  • Other Name:

    CNOT7; CAF1; CCR4-NOT transcription complex subunit 7; BTG1-binding factor 1; CCR4-associated factor 1; CAF-1
  • Observed Band(KD):

    36
  • Background:

    CCR4-NOT transcription complex subunit 7(CNOT7) Homo sapiens The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016],
  • Function:

    function:Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.,similarity:Belongs to the CAF1 family.,subunit:Interacts with TOB1.,
  • Subcellular Location:

    Nucleus. Cytoplasm, P-body . NANOS2 promotes its localization to P-body. .
  • Expression:

    Embryo,Lymph,Placenta,Prostate,Testis,Products Images
  • Western blot analysis of lysates from HeLa and HUVEC cells, using CNOT7 Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

Add to Cart

AbPromise
CNOT7 Polyclonal Antibody | EnoGene Biotech Co. Ltd