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CLIP-170 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70968
  • Amount:

    100ul
  • Molecular Weight:

    160990Da
  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA
  • Reactivity:

    Human;Mouse
  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CLIP1. AA range:1291-1340
  • Source:

    Polyclonal, Rabbit,IgG
  • Western Blot analysis of various cells using CLIP-170 Polyclonal Antibody
  • Gene Name:

    CLIP1
  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
  • Protein Name:

    CAP-Gly domain-containing linker protein 1
  • Human Gene Id:

    6249
  • Human Swiss Prot No:

    P30622
  • Mouse Gene Id:

    56430
  • Mouse Swiss Prot No:

    Q922J3
  • Specificity:

    CLIP-170 Polyclonal Antibody detects endogenous levels of CLIP-170 protein.
  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Concentration:

    1 mg/ml
  • Storage Stability:

    -20°C/1 year
  • Other Name:

    CLIP1; CYLN1; RSN; CAP-Gly domain-containing linker protein 1; Cytoplasmic linker protein 1; Cytoplasmic linker protein 170 alpha-2; CLIP-170; Reed-Sternberg intermediate filament-associated protein; Restin
  • Observed Band(KD):

    161
  • Background:

    The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
  • Function:

    function:Seems to be a intermediate filament associated protein that links endocytic vesicles to microtubules.,similarity:Contains 2 CAP-Gly domains.,subcellular location:Associated with the cytoskeleton.,tissue specificity:Highly expressed in the Reed-Sternberg cells of Hodgkin's disease.,
  • Subcellular Location:

    Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasmic vesicle membrane ; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle . Localizes to microtubule plus ends (PubMed:21646404, PubMed:17889670). Localizes preferentially to the ends of tyrosinated microtubules (By similarity). Accumulates in plasma membrane regions with ruffling and protrusions. Associates with the membranes of intermediate macropinocytic vesicles (PubMed:12433698). .
  • Expression:

    Detected in dendritic cells (at protein level). Highly expressed in the Reed-Sternberg cells of Hodgkin disease.Products Images
  • Western Blot analysis of RAW264.7 cells using CLIP-170 Polyclonal Antibody

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Catalog Number

  • Amount:100ul
  • Price:225$

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AbPromise
CLIP-170 Polyclonal Antibody | EnoGene Biotech Co. Ltd