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CLC-6 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70960

  • Amount:

    100ul

  • Molecular Weight:

    97217Da

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Mouse

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CLCN6. AA range:611-660

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using CLC-6 Polyclonal Antibody diluted at 1:500

  • Gene Name:

    CLCN6

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

  • Protein Name:

    Chloride transport protein 6

  • Human Gene Id:

    1185

  • Human Swiss Prot No:

    P51797

  • Mouse Gene Id:

    26372

  • Mouse Swiss Prot No:

    O35454

  • Specificity:

    CLC-6 Polyclonal Antibody detects endogenous levels of CLC-6 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CLCN6; KIAA0046; Chloride transport protein 6; Chloride channel protein 6; ClC-6

  • Observed Band(KD):

    97

  • Background:

    chloride voltage-gated channel 6(CLCN6) Homo sapiens This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown. [provided by RefSeq, Mar 2012],

  • Function:

    function:Chloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter.,miscellaneous:The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters.,PTM:N-glycosylated on several asparagine residues.,similarity:Belongs to the chloride channel (TC 2.A.49) family.,similarity:Contains 2 CBS domains.,subcellular location:Detected in detergent-resistant lipid rafts.,tissue specificity:Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform C is only detected in kidney.,

  • Subcellular Location:

    Late endosome membrane ; Multi-pass membrane protein .

  • Expression:

    Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney.Products Images

  • Western Blot analysis of L929 cells using CLC-6 Polyclonal Antibody diluted at 1:500

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Catalog Number

  • Amount:100ul
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CLC-6 Polyclonal Antibody | EnoGene Biotech Co. Ltd