World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
CKR-7 Polyclonal Antibody Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight42874Da
Protein NameC-C chemokine receptor type 7
Human Gene Id1236
Human Swiss Prot NoP32248
Mouse Swiss Prot NoP47774
SpecificityCKR-7 Polyclonal Antibody detects endogenous levels of CKR-7 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCCR7; CMKBR7; EBI1; EVI1; C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; BLR2; CDw197; Epstein-Barr virus-induced G-protein coupled receptor 1; EBI1; EBV-induced G-protein coupled receptor 1; MIP-3 beta receptor; CD antigen CD19
Observed Band(KD)43
Functionfunction:Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.,induction:By EBV.,online information:CC chemokine receptors entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.,
Subcellular Locationintracellular,plasma membrane,external side of plasma membrane,cell surface,integral component of membrane,
ExpressionBrain,Placenta,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CCR7. AA range:170-219
Gene NameCCR7
DilutionWestern Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
BackgroundC-C motif chemokine receptor 7(CCR7) Homo sapiens The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-70938-Conjugate. Price: $485 / Size: 100μl.
E20-70938-FITC$485 / 100μlE20-70938-Biotin$485 / 100μlE20-70938-HRP$485 / 100μlE20-70938-AP$485 / 100μlE20-70938-AF350$485 / 100μlE20-70938-AF405M$485 / 100μlE20-70938-AF488$485 / 100μlE20-70938-AF514$485 / 100μlE20-70938-AF532$485 / 100μlE20-70938-AF555$485 / 100μlE20-70938-AF568$485 / 100μlE20-70938-AF405S$485 / 100μlE20-70938-AF405L$485 / 100μlE20-70938-AF546$485 / 100μlE20-70938-AF594$485 / 100μlE20-70938-AF610$485 / 100μlE20-70938-AF635$485 / 100μlE20-70938-AF647$485 / 100μlE20-70938-AF680$485 / 100μlE20-70938-AF700$485 / 100μlE20-70938-AF750$485 / 100μlE20-70938-AF790$485 / 100μlE20-70938-APC$485 / 100μlE20-70938-PE$485 / 100μlE20-70938-Cy3$485 / 100μlE20-70938-Cy5$485 / 100μlE20-70938-Cy5.5$485 / 100μlE20-70938-Cy7$485 / 100μlE20-70938-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits