CHP Polyclonal Antibody

Name: CHP Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-70914
Price: 225 USD
Availability: InStock

E20-70914Cite ID: EN0051047Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight22456DaObserved Band:24KD

Protein NameCalcineurin B homologous protein 1

Human Gene Id11261

Human Swiss Prot NoQ99653

Mouse Gene Id56398

Mouse Swiss Prot NoP61022

Rat Gene Id64152

Rat Swiss Prot NoP61023

SpecificityCHP Polyclonal Antibody detects endogenous levels of CHP protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameCHP1; CHP; Calcineurin B homologous protein 1; Calcineurin B-like protein; Calcium-binding protein CHP; Calcium-binding protein p22; EF-hand calcium-binding domain-containing protein p22

Functionfunction:Required for constitutive membrane traffic. Inhibits GTPase-stimulated Na(+)/H(+) exchange. Also inhibits calcineurin phosphatase activity. Required for activity of SLC9A1/NHE1.,PTM:Both N-myristoylation and calcium-mediated conformational changes are essential for its function in exocytic traffic.,PTM:Phosphorylated; decreased phosphorylation is associated with an increase in exchange activity. The phosphorylation state may regulate the binding to NHE1.,similarity:Contains 4 EF-hand domains.,subunit:Monomer (By similarity). Specifically binds to SLC9A1/NHE1 at a domain that is critical for growth factor stimulation of exchange activity.,tissue specificity:Ubiquitously expressed. Has been found in fetal eye, lung, liver, muscle, heart, kidney, thymus and spleen.,

Subcellular LocationGolgi membrane,nucleus,cytoplasm,endoplasmic reticulum,endoplasmic reticulum-Golgi intermediate compartment,cytosol,plasma membrane,focal adhesion,microtubule cytoskeleton,transport vesicle,extracellular exosome,

ExpressionB-cell,Brain,Uterus,,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenSynthesized peptide derived from the Internal region of human CHP.

Gene NameCHP1

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Backgroundcalcineurin like EF-hand protein 1(CHP1) Homo sapiens This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-70914-Conjugate. Price: $485 / Size: 100μl.

E20-70914-FITC$485 / 100μlE20-70914-Biotin$485 / 100μlE20-70914-HRP$485 / 100μlE20-70914-AP$485 / 100μlE20-70914-AF350$485 / 100μlE20-70914-AF405M$485 / 100μlE20-70914-AF488$485 / 100μlE20-70914-AF514$485 / 100μlE20-70914-AF532$485 / 100μlE20-70914-AF555$485 / 100μlE20-70914-AF568$485 / 100μlE20-70914-AF405S$485 / 100μlE20-70914-AF405L$485 / 100μlE20-70914-AF546$485 / 100μlE20-70914-AF594$485 / 100μlE20-70914-AF610$485 / 100μlE20-70914-AF635$485 / 100μlE20-70914-AF647$485 / 100μlE20-70914-AF680$485 / 100μlE20-70914-AF700$485 / 100μlE20-70914-AF750$485 / 100μlE20-70914-AF790$485 / 100μlE20-70914-APC$485 / 100μlE20-70914-PE$485 / 100μlE20-70914-Cy3$485 / 100μlE20-70914-Cy5$485 / 100μlE20-70914-Cy5.5$485 / 100μlE20-70914-Cy7$485 / 100μlE20-70914-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.