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cGKII Polyclonal Antibody
Datasheet
Catalog Number:
E20-70891Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human PKG2. AA range:92-141Source:
Polyclonal, Rabbit
- Western Blot analysis of A549 cells using cGKII Polyclonal Antibody diluted at 1:1000
Gene Name:
PRKG2Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.Background:
protein kinase, cGMP-dependent, type II(PRKG2) Homo sapiens This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],Protein Name:
cGMP-dependent protein kinase 2Human Gene Id:
5593Human Swiss Prot No:
13237Specificity:
cGKII Polyclonal Antibody detects endogenous levels of cGKII protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
PRKG2; PRKGR2; cGMP-dependent protein kinase 2; cGK 2; cGK2; cGMP-dependent protein kinase II; cGKIIMolecularWeight(Da):
87432Observed Band(KD):
87Function:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Binding of cGMP results in enzyme activation.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 cyclic nucleotide-binding domains.,tissue specificity:Highly concentrated in brain, lung and intestinal mucosa.,Subcellular Location:
cytosol,apical plasma membrane,nuclear membrane,Expression:
Pituitary,
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