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CUX1 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70845

  • Amount:

    100ul

  • Molecular Weight:

    164273Da

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Mouse

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CUTL1. AA range:10-59

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using CUX1 Polyclonal Antibody diluted at 1:1000

  • Gene Name:

    CUX1

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

  • Protein Name:

    Homeobox protein cut-like 1/Protein CASP

  • Human Gene Id:

    1523

  • Human Swiss Prot No:

    P39880/Q13948

  • Mouse Gene Id:

    13047/13047

  • Specificity:

    CUX1 Polyclonal Antibody detects endogenous levels of CUX1 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CUX1; CUTL1; Homeobox protein cut-like 1; CCAAT displacement protein; CDP; Homeobox protein cux-1; CUX1; CUTL1; Protein CASP

  • Observed Band(KD):

    164

  • Background:

    The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011],

  • Function:

    alternative products:Additional isoforms seem to exist,function:May be involved in intra-Golgi retrograde transport.,function:Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer.,miscellaneous:Asn-1290 may participate in regulating DNA-binding activity by promoting homo- and heterodimerization.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CASP family.,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 homeobox DNA-bin

  • Subcellular Location:

    Nucleus .

  • Expression:

    Colon,Duodenum,Liver,Umbilical vein,

  • Western Blot analysis of 293T cells using CUX1 Polyclonal Antibody diluted at 1:1000

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Catalog Number

  • Amount:100ul
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CUX1 Polyclonal Antibody | EnoGene Biotech Co. Ltd