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CDHF10 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70825

  • Amount:

    100ul

  • Molecular Weight:

    317453Da

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CELSR2. AA range:2781-2830

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    CELSR2

  • Dilution:

    Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

  • Immunofluorescence analysis of COS7 cells, using CELSR2 Antibody. The picture on the right is blocked with the synthesized peptide.

  • Protein Name:

    Cadherin EGF LAG seven-pass G-type receptor 2

  • Human Gene Id:

    1952

  • Human Swiss Prot No:

    Q9HCU4

  • Specificity:

    CDHF10 Polyclonal Antibody detects endogenous levels of CDHF10 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CELSR2; CDHF10; EGFL2; KIAA0279; MEGF3; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; Epidermal growth factor-like protein 2; EGF-like protein 2; Flamingo homolog 3; Multiple epidermal growth factor-like domains

  • Background:

    cadherin EGF LAG seven-pass G-type receptor 2(CELSR2) Homo sapiens The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008],

  • Function:

    function:Receptor that may have an important role in cell/cell signaling during nervous system formation.,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 laminin EGF-like domain.,similarity:Contains 2 laminin G-like domains.,similarity:Contains 7 EGF-like domains.,similarity:Contains 9 cadherin domains.,tissue specificity:Highest expression in brain and testis.,

  • Subcellular Location:

    cytoplasm,plasma membrane,integral component of membrane,

  • Expression:

    Brain,

  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CELSR2 Antibody. The picture on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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CDHF10 Polyclonal Antibody | EnoGene Biotech Co. Ltd