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CdcA3 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70819
  • Amount:

    100ul
  • Molecular Weight:

    28998Da
  • Applications:

    WB;IHC-p;IF/ICC;ELISA
  • Reactivity:

    Human;Mouse;Rat
  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268
  • Source:

    Polyclonal, Rabbit,IgG
  • Western Blot analysis of various cells using CdcA3 Polyclonal Antibody
  • Gene Name:

    CDCA3
  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
  • Protein Name:

    Cell division cycle-associated protein 3
  • Human Gene Id:

    83461
  • Human Swiss Prot No:

    Q99618
  • Mouse Gene Id:

    14793
  • Mouse Swiss Prot No:

    Q99M54
  • Rat Gene Id:

    297594
  • Rat Swiss Prot No:

    Q68FW2
  • Specificity:

    CdcA3 Polyclonal Antibody detects endogenous levels of CdcA3 protein.
  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Concentration:

    1 mg/ml
  • Storage Stability:

    -20°C/1 year
  • Other Name:

    CDCA3; C8; GRCC8; TOME1; Cell division cycle-associated protein 3; Gene-rich cluster protein C8; Trigger of mitotic entry protein 1; TOME-1
  • Observed Band(KD):

    28
  • Background:

    domain:The KEN box is required for the association with the APC/C-Cdh1 complex.,function:F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex.,subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,
  • Function:

    domain:The KEN box is required for the association with the APC/C-Cdh1 complex.,function:F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex.,subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,
  • Subcellular Location:

    Cytoplasm, cytosol .
  • Expression:

    Brain,Placenta,Testis,Thymus,
  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using CDCA3 Antibody. The picture on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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AbPromise
CdcA3 Polyclonal Antibody | EnoGene Biotech Co. Ltd