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Cell Signal Transduction Research Antibodies
Cdc42EP3 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight27678 Da
Protein NameCdc42 effector protein 3
Human Gene Id10602
Human Swiss Prot NoQ9UKI2
Mouse Gene Id260409
Mouse Swiss Prot NoQ9CQC5
SpecificityCdc42EP3 Polyclonal Antibody detects endogenous levels of Cdc42EP3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCDC42EP3; BORG2; CEP3; Cdc42 effector protein 3; Binder of Rho GTPases 2; MSE55-related Cdc42-binding protein
Observed Band(KD)26
Functionfunction:Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.,similarity:Belongs to the BORG/CEP family.,similarity:Contains 1 CRIB domain.,subunit:Interacts with RHOQ and CDC42, in a GTP-dependent manner, and with SEPT7.,tissue specificity:Highly expressed in the heart and weakly in the brain.,
Subcellular Locationcytoplasm,cytosol,plasma membrane,endomembrane system,actin cytoskeleton,
ExpressionBrain,Epithelium,Heart,Lung,Testis,Uterus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenSynthesized peptide derived from the N-terminal region of human Cdc42EP3.
Gene NameCDC42EP3
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
BackgroundCDC42 effector protein 3(CDC42EP3) Homo sapiens This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],
Conjugated Antibody
This product is also available conjugated. Format: E20-70809-Conjugate. Price: $485 / Size: 100μl.
E20-70809-FITC$485 / 100μlE20-70809-Biotin$485 / 100μlE20-70809-HRP$485 / 100μlE20-70809-AP$485 / 100μlE20-70809-AF350$485 / 100μlE20-70809-AF405M$485 / 100μlE20-70809-AF488$485 / 100μlE20-70809-AF514$485 / 100μlE20-70809-AF532$485 / 100μlE20-70809-AF555$485 / 100μlE20-70809-AF568$485 / 100μlE20-70809-AF405S$485 / 100μlE20-70809-AF405L$485 / 100μlE20-70809-AF546$485 / 100μlE20-70809-AF594$485 / 100μlE20-70809-AF610$485 / 100μlE20-70809-AF635$485 / 100μlE20-70809-AF647$485 / 100μlE20-70809-AF680$485 / 100μlE20-70809-AF700$485 / 100μlE20-70809-AF750$485 / 100μlE20-70809-AF790$485 / 100μlE20-70809-APC$485 / 100μlE20-70809-PE$485 / 100μlE20-70809-Cy3$485 / 100μlE20-70809-Cy5$485 / 100μlE20-70809-Cy5.5$485 / 100μlE20-70809-Cy7$485 / 100μlE20-70809-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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