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CD88 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70781
  • Amount:

    100ul
  • Molecular Weight:

    39321Da
  • Applications:

    WB;IHC-p;IF/ICC;ELISA
  • Reactivity:

    Human;Rat;Mouse;
  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human N ternal CD88/C5aR. AA range:301-350
  • Source:

    Polyclonal, Rabbit,IgG
  • Western Blot analysis of various cells using CD88 Polyclonal Antibody
  • Gene Name:

    C5AR1
  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
  • Protein Name:

    C5a anaphylatoxin chemotactic receptor
  • Human Gene Id:

    728
  • Human Swiss Prot No:

    P21730
  • Mouse Swiss Prot No:

    P30993
  • Specificity:

    CD88 Polyclonal Antibody detects endogenous levels of CD88 protein.
  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Concentration:

    1 mg/ml
  • Storage Stability:

    -20°C/1 year
  • Other Name:

    C5AR1; C5AR; C5R1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD antigen CD88
  • Observed Band(KD):

    45
  • Background:

    function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,
  • Function:

    function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,
  • Subcellular Location:

    Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle . Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. .
  • Expression:

    Brain,
  • Immunofluorescence analysis of HeLa cells, using CD88/C5aR Antibody. The picture on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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