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Cell Signal Transduction Research Antibodies
CD85c Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight64126Da
Protein NameLeukocyte immunoglobulin-like receptor subfamily B member 5
Human Gene Id10990
Human Swiss Prot NoO75023
SpecificityCD85c Polyclonal Antibody detects endogenous levels of CD85c protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameLILRB5; LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD85c
Observed Band(KD)65
Functiondomain:Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.,function:May act as receptor for class I MHC antigens.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Detected in a natural killer (NK) cells.,
Subcellular Locationintegral component of membrane,
ExpressionPancreas,Peripheral blood leukocyte,Plasma,Small intestine,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from the N-terminal region of human LILRB5. AA range:21-70
Gene NameLILRB5
DilutionWestern Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Backgroundleukocyte immunoglobulin like receptor B5(LILRB5) Homo sapiens This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-70780-Conjugate. Price: $485 / Size: 100μl.
E20-70780-FITC$485 / 100μlE20-70780-Biotin$485 / 100μlE20-70780-HRP$485 / 100μlE20-70780-AP$485 / 100μlE20-70780-AF350$485 / 100μlE20-70780-AF405M$485 / 100μlE20-70780-AF488$485 / 100μlE20-70780-AF514$485 / 100μlE20-70780-AF532$485 / 100μlE20-70780-AF555$485 / 100μlE20-70780-AF568$485 / 100μlE20-70780-AF405S$485 / 100μlE20-70780-AF405L$485 / 100μlE20-70780-AF546$485 / 100μlE20-70780-AF594$485 / 100μlE20-70780-AF610$485 / 100μlE20-70780-AF635$485 / 100μlE20-70780-AF647$485 / 100μlE20-70780-AF680$485 / 100μlE20-70780-AF700$485 / 100μlE20-70780-AF750$485 / 100μlE20-70780-AF790$485 / 100μlE20-70780-APC$485 / 100μlE20-70780-PE$485 / 100μlE20-70780-Cy3$485 / 100μlE20-70780-Cy5$485 / 100μlE20-70780-Cy5.5$485 / 100μlE20-70780-Cy7$485 / 100μlE20-70780-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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