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CD83 Polyclonal Antibody
Datasheet
Catalog Number:
E20-70779Amount:
100ulMolecular Weight:
23042DaApplications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;Rat;Mouse;Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human CD83. AA range:101-150Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using CD83 Polyclonal Antibody diluted at 1:500
Gene Name:
CD83Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.Protein Name:
CD83 antigenHuman Gene Id:
9308Human Swiss Prot No:
Q01151Mouse Swiss Prot No:
O88324Specificity:
CD83 Polyclonal Antibody detects endogenous levels of CD83 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
CD83; CD83 antigen; hCD83; B-cell activation protein; Cell surface protein HB15; CD antigen CD83Observed Band(KD):
23Background:
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],Function:
function:May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.,online information:CD83 antigen,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Monomer.,tissue specificity:Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.,Subcellular Location:
Membrane; Single-pass type I membrane protein.Expression:
Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.
- Immunohistochemical analysis of paraffin-embedded Human kidney. 1, Antibody was diluted at 1:400(4° overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
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