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CD70 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70774

  • Amount:

    100ul

  • Molecular Weight:

    21118Da

  • Applications:

    WB;ELISA

  • Reactivity:

    Human;Rat;Mouse;

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CD70. AA range:68-117

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using CD70 Polyclonal Antibody diluted at 1:2000

  • Gene Name:

    CD70

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

  • Protein Name:

    CD70 antigen

  • Human Gene Id:

    970

  • Human Swiss Prot No:

    P32970

  • Mouse Swiss Prot No:

    O55237

  • Specificity:

    CD70 Polyclonal Antibody detects endogenous levels of CD70 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CD70; CD27L; CD27LG; TNFSF7; CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD antigen CD70

  • Observed Band(KD):

    30

  • Background:

    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008],

  • Function:

    function:Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer.,

  • Subcellular Location:

    Membrane ; Single-pass type II membrane protein .

  • Expression:

    B-cell,Kidney,

  • Western blot analysis of the lysates from Jurkat cells using CD70 antibody.

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Catalog Number

  • Amount:100ul
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