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CD58 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70770

  • Amount:

    100ul

  • Molecular Weight:

    28147Da

  • Applications:

    WB;IHC-p;IF(paraffin section);ELISA

  • Reactivity:

    Human;Rat;Mouse;

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from the Internal region of human CD58. AA range:31-80

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of K562 cells using CD58 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000

  • Gene Name:

    CD58

  • Dilution:

    Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

  • Protein Name:

    Lymphocyte function-associated antigen 3

  • Human Gene Id:

    965

  • Human Swiss Prot No:

    P19256

  • Specificity:

    CD58 Polyclonal Antibody detects endogenous levels of CD58 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CD58; LFA3; Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58

  • Observed Band(KD):

    27

  • Background:

    This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009],

  • Function:

    function:Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,

  • Subcellular Location:

    [Isoform 1]: Cell membrane; Single-pass type I membrane protein.

  • Expression:

    Brain,Erythrocyte,

  • Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100

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