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CD34 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70757

  • Amount:

    100ul

  • Molecular Weight:

    40716Da

  • Applications:

    WB;IHC-p;IF/ICC;ELISA

  • Reactivity:

    Human;Mouse;

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CD34. AA range:208-257

  • Source:

    Polyclonal, Rabbit,IgG

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  • Gene Name:

    CD34

  • Dilution:

    WB 1:500-2000;IHC-p 1:100-500;IF/ICC 1:100-500;ELISA 1:5000-20000

  • Protein Name:

    Hematopoietic progenitor cell antigen CD34

  • Human Gene Id:

    947

  • Human Swiss Prot No:

    P28906

  • Mouse Gene Id:

    12490

  • Mouse Swiss Prot No:

    Q64314

  • Specificity:

    CD34 Polyclonal Antibody detects endogenous levels of CD34 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CD34; Hematopoietic progenitor cell antigen CD34; CD antigen CD34

  • Observed Band(KD):

    110

  • Background:

    The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

  • Function:

    alternative products:Both isoforms are expressed on the cell surface. CD34-T/CD34-F ratio increases with cell differentiation,developmental stage:On early hematopoietic progenitor cells.,disease:Abnormal CD34 expression in leukemogenesis.,function:Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.,online information:CD34 entry,PTM:Highly glycosylated.,PTM:Phosphorylated on serine residues by PKC.,similarity:Belongs to the CD34 family.,tissue specificity:Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tiss

  • Subcellular Location:

    Membrane; Single-pass type I membrane protein.

  • Expression:

    Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.

  • Immunohistochemical analysis of paraffin-embedded Human colon. 1, Antibody was diluted at 1:200(4° overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

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Catalog Number

  • Amount:100ul
  • Price:225$

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CD34 Polyclonal Antibody | EnoGene Biotech Co. Ltd