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CD2BP2 Polyclonal Antibody
Datasheet
Catalog Number:
E20-70746Amount:
100ulMolecular Weight:
37646DaApplications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;MonkeyPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human CD2 Tail-binding. AA range:101-150Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of various cells using CD2BP2 Polyclonal Antibody diluted at 1:1000
Gene Name:
CD2BP2Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.Protein Name:
CD2 antigen cytoplasmic tail-binding protein 2Human Gene Id:
10421Human Swiss Prot No:
O95400Mouse Swiss Prot No:
Q9CWK3Specificity:
CD2BP2 Polyclonal Antibody detects endogenous levels of CD2BP2 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
CD2BP2; KIAA1178; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2Observed Band(KD):
50Background:
This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008],Function:
similarity:Contains 1 GYF domain.,subunit:Binds the cytoplasmic domain of CD2 through the GYF domain.,Subcellular Location:
Cytoplasm. Nucleus. Predominantly nuclear.Expression:
Aorta,Brain,Epithelium,Liver,Lung,
- Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
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