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CD206 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70739

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human MRC1. AA range:643-692

  • Source:

    Polyclonal, Rabbit

  • Western Blot analysis of 3T3 cells using CD206 Polyclonal Antibody diluted at 1:1000

  • Gene Name:

    MRC1

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

  • Background:

    mannose receptor, C type 1(MRC1) Homo sapiens The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015],

  • Protein Name:

    Macrophage mannose receptor 1

  • Human Gene Id:

    4360

  • Human Swiss Prot No:

    P22897

  • Mouse Gene Id:

    17533

  • Mouse Swiss Prot No:

    Q61830

  • Specificity:

    CD206 Polyclonal Antibody detects endogenous levels of CD206 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    MRC1; CLEC13D; CLEC13DL; MRC1L1; Macrophage mannose receptor 1; MMR; C-type lectin domain family 13 member D; C-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD antigen CD206

  • MolecularWeight(Da):

    166012

  • Observed Band(KD):

    166

  • Function:

    function:Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.,miscellaneous:CRDs 1-3 have at most very weak affinity for carbohydrate. CRD 4 shows the highest affinity binding and has multispecificity for a variety of monosaccharides. At least 3 CRDs (4, 5, and 7) are required for high affinity binding and endocytosis of multivalent glycoconjugates.,online information:Macrophage mannose receptor,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 ricin B-type lectin domain.,similarity:Contains 8 C-type lectin domains.,

  • Subcellular Location:

    plasma membrane,integral component of plasma membrane,cell surface,endosome membrane,

  • Expression:

    Milk,Placenta,Testis,

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Catalog Number

  • Amount:100ul
  • Price:225$

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