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CD172g Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70733

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human SIRPG. AA range:101-150

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    SIRPG

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

  • Western blot analysis of lysates from COS cells, using SIRPG Antibody. The lane on the right is blocked with the synthesized peptide.

  • Background:

    signal regulatory protein gamma(SIRPG) Homo sapiens The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

  • Protein Name:

    Signal-regulatory protein gamma

  • Human Gene Id:

    55423

  • Human Swiss Prot No:

    Q9P1W8

  • Specificity:

    CD172g Polyclonal Antibody detects endogenous levels of CD172g protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    SIRPG; SIRPB2; Signal-regulatory protein gamma; SIRP-gamma; CD172 antigen-like family member B; Signal-regulatory protein beta-2; SIRP-b2; SIRP-beta-2; CD antigen CD172g

  • MolecularWeight(Da):

    41595

  • Observed Band(KD):

    42

  • Function:

    function:Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like C1-type (immunoglobulin-like) domains.,subunit:Interacts with CD47.,tissue specificity:Detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. Mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, primarily expressed in the medulla on mature T

  • Subcellular Location:

    intracellular,plasma membrane,membrane,integral component of membrane,

  • Expression:

    Lung,Ovary,Placenta,T-cell,

  • Western blot analysis of the lysates from RAW264.7cells using SIRPG antibody.

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Catalog Number

  • Amount:100ul
  • Price:225$

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CD172g Polyclonal Antibody | EnoGene Biotech Co. Ltd