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CD138 Polyclonal Antibody
Datasheet
Catalog Number:
E20-70724Amount:
100ulMolecular Weight:
32462DaApplications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;Rat;Mouse;Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human SDC1. AA range:191-240Source:
Polyclonal, Rabbit,IgG
- Western Blot analysis of 293 cells using CD138 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Gene Name:
SDC1Dilution:
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.Protein Name:
Syndecan-1Human Gene Id:
6382Human Swiss Prot No:
P18827Mouse Swiss Prot No:
P18828Specificity:
CD138 Polyclonal Antibody detects endogenous levels of CD138 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
SDC1; SDC; Syndecan-1; SYND1; CD138Observed Band(KD):
34Background:
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008],Function:
function:Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Interacts with CDCP1.,Subcellular Location:
Membrane ; Single-pass type I membrane protein . Secreted . Secreted, extracellular exosome . Shedding of the ectodomain produces a soluble form. .Expression:
Dermoid cancer,Fibroblast,Kidney,Mammary gland,Placenta,
- Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:100
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