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CD137L Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70723

  • Amount:

    100ul

  • Molecular Weight:

    26625Da

  • Applications:

    WB;IF/ICC;ELISA

  • Reactivity:

    Human;Rat;Mouse;

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human TNFSF9. AA range:31-80

  • Source:

    Polyclonal, Rabbit,IgG

  • Western Blot analysis of various cells using CD137L Polyclonal Antibody diluted at 1:1000

  • Gene Name:

    TNFSF9

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

  • Protein Name:

    Tumor necrosis factor ligand superfamily member 9

  • Human Gene Id:

    8744

  • Human Swiss Prot No:

    P41273

  • Mouse Swiss Prot No:

    P41274

  • Specificity:

    CD137L Polyclonal Antibody detects endogenous levels of CD137L protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    TNFSF9; Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL

  • Observed Band(KD):

    23

  • Background:

    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided b

  • Function:

    function:Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer .,tissue specificity:Expressed in brain, placenta, lung, skeletal muscle and kidney.,

  • Subcellular Location:

    Membrane; Single-pass type II membrane protein.

  • Expression:

    Expressed in brain, placenta, lung, skeletal muscle and kidney.

  • Western Blot analysis of HuvEc cells using CD137L Polyclonal Antibody diluted at 1:1000

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Catalog Number

  • Amount:100ul
  • Price:225$

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CD137L Polyclonal Antibody | EnoGene Biotech Co. Ltd