World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
CB1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight52858DaObserved Band:53KD
Protein NameCannabinoid receptor 1
Human Gene Id1268
Human Swiss Prot NoP21554
Mouse Gene Id12801
Mouse Swiss Prot NoP47746
Rat Gene Id25248
Rat Swiss Prot NoP20272
SpecificityCB1 Polyclonal Antibody detects endogenous levels of CB1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCNR1; CNR; Cannabinoid receptor 1; CB-R; CB1; CANN6
Functionfunction:Involved in cannabinoid-induced CNS effects. Acts by inhibiting adenylate cyclase. Could be a receptor for anandamide. Inhibits L-type Ca(2+) channel current. Isoform 2 and isoform 3 have altered ligand binding.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts (via C-terminus) with CNRIP1.,tissue specificity:Widely expressed.,
Subcellular Locationplasma membrane,integral component of plasma membrane,integral component of membrane,axon,growth cone,intracellular membrane-bounded organelle,membrane raft,
ExpressionBrain,Brain stem,Brain tumor,Hippocampus,Lung,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CNR1. AA range:151-200
Gene NameCNR1
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundcannabinoid receptor 1(CNR1) Homo sapiens This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-70687-Conjugate. Price: $485 / Size: 100μl.
E20-70687-FITC$485 / 100μlE20-70687-Biotin$485 / 100μlE20-70687-HRP$485 / 100μlE20-70687-AP$485 / 100μlE20-70687-AF350$485 / 100μlE20-70687-AF405M$485 / 100μlE20-70687-AF488$485 / 100μlE20-70687-AF514$485 / 100μlE20-70687-AF532$485 / 100μlE20-70687-AF555$485 / 100μlE20-70687-AF568$485 / 100μlE20-70687-AF405S$485 / 100μlE20-70687-AF405L$485 / 100μlE20-70687-AF546$485 / 100μlE20-70687-AF594$485 / 100μlE20-70687-AF610$485 / 100μlE20-70687-AF635$485 / 100μlE20-70687-AF647$485 / 100μlE20-70687-AF680$485 / 100μlE20-70687-AF700$485 / 100μlE20-70687-AF750$485 / 100μlE20-70687-AF790$485 / 100μlE20-70687-APC$485 / 100μlE20-70687-PE$485 / 100μlE20-70687-Cy3$485 / 100μlE20-70687-Cy5$485 / 100μlE20-70687-Cy5.5$485 / 100μlE20-70687-Cy7$485 / 100μlE20-70687-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits