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Cardiotrophin-1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-70638Amount:
100ulMolecular Weight:
21227DaApplications:
WB;IHC-p;IF(paraffin section);ELISAReactivity:
Human;Mouse;RatPurification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human Cardiotrophin-1. AA range:31-80Source:
Polyclonal, Rabbit,IgG
- Immunohistochemistry analysis of Cardiotrophin-1 antibody in paraffin-embedded human lung carcinoma tissue.
Gene Name:
CTF1Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.Protein Name:
Cardiotrophin-1Human Gene Id:
1489Human Swiss Prot No:
Q16619Mouse Gene Id:
13019Mouse Swiss Prot No:
Q60753Rat Gene Id:
29201Rat Swiss Prot No:
Q63086Specificity:
Cardiotrophin-1 Polyclonal Antibody detects endogenous levels of Cardiotrophin-1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
CTF1; Cardiotrophin-1; CT-1Observed Band(KD):
21Background:
The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],Function:
function:Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.,similarity:Belongs to the IL-6 superfamily.,tissue specificity:Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes.,Subcellular Location:
Secreted.Expression:
Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes.
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