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CaMKIβ Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70629

  • Amount:

    100ul

  • Molecular Weight:

    38500Da

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CaMK1-beta. AA range:161-210

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    PNCK

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CaMK1-beta Antibody. The picture on the right is blocked with the synthesized peptide.

  • Protein Name:

    Calcium/calmodulin-dependent protein kinase type 1B

  • Human Gene Id:

    139728

  • Human Swiss Prot No:

    Q6P2M8

  • Mouse Gene Id:

    93843

  • Mouse Swiss Prot No:

    Q9QYK9

  • Rat Gene Id:

    29660

  • Rat Swiss Prot No:

    O70150

  • Specificity:

    CaMKIβ Polyclonal Antibody detects endogenous levels of CaMKIβ protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    PNCK; Calcium/calmodulin-dependent protein kinase type 1B; CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMKI-beta; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase

  • Observed Band(KD):

    38

  • Background:

    pregnancy up-regulated nonubiquitous CaM kinase(PNCK) Homo sapiens PNCK is a member of the calcium/calmodulin-dependent protein kinase family of protein serine/threonine kinases (see CAMK1; MIM 604998) (Gardner et al., 2000 [PubMed 10673339]).[supplied by OMIM, Mar 2008],

  • Function:

    catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by Ca(2+)/calmodulin.,function:Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates CREB1 and SYN1/synapsin I. Phosphorylates and activates CAMK1.,PTM:Phosphorylated by CAMKK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,

  • Subcellular Location:

    nucleus,cytoplasm,

  • Expression:

    Brain,Liver,Placenta,Thalamus,

  • Western blot analysis of lysates from LOVO cells, treated with H2O2 100uM 30', using CaMK1-beta Antibody. The lane on the right is blocked with the synthesized peptide.

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