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CaMKIIβ/γ Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-70625

  • Amount:

    100ul

  • Molecular Weight:

    62609Da

  • Applications:

    WB;IF/ICC;ELISA

  • Reactivity:

    Human;Mouse;Rat

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human CaMK2 beta/gamma. AA range:509-558

  • Source:

    Polyclonal, Rabbit,IgG

  • Western blot analysis of lysates from COLO205 and Jurkat cells, using CaMK2 beta/gamma Antibody. The lane on the right is blocked with the synthesized peptide.

  • Gene Name:

    CAMK2B/CAMK2G

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

  • Protein Name:

    Calcium/calmodulin-dependent protein kinase type II subunit beta/gamma

  • Human Gene Id:

    818/816

  • Human Swiss Prot No:

    Q13555/Q13554

  • Mouse Gene Id:

    12325/12323

  • Rat Gene Id:

    171140/24245

  • Rat Swiss Prot No:

    P11730/P08413

  • Specificity:

    CaMKIIβ/γ Polyclonal Antibody detects endogenous levels of CaMKIIβ/γ protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II subunit gamma; CaMK-II subunit gamma; CAMK2B; CAM2; CAMK2; CAMKB; Calcium/calmodulin-dependent protein kinase type II subunit bet

  • Observed Band(KD):

    62

  • Background:

    The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011],

  • Function:

    catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Autophosphorylation of CAMK2 plays an important role in the regulation of the kinase activity.,function:CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,subunit:CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.,

  • Subcellular Location:

    Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side .

  • Expression:

    Expressed in skeletal muscle.

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Catalog Number

  • Amount:100ul
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CaMKIIβ/γ Polyclonal Antibody | EnoGene Biotech Co. Ltd