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Cell Signal Transduction Research Antibodies
Calpain 9 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight79097Da
Protein NameCalpain-9
Human Gene Id10753
Human Swiss Prot NoO14815
Mouse Swiss Prot NoQ9D805
SpecificityCalpain 9 Polyclonal Antibody detects endogenous levels of Calpain 9 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCAPN9; NCL4; Calpain-9; Digestive tract-specific calpain; New calpain 4; nCL-4; Protein CG36
Observed Band(KD)75
Functioncatalytic activity:Broad endopeptidase specificity.,function:Calcium-regulated non-lysosomal thiol-protease.,induction:Down-regulated in gastric cancer tissue and in gastric cell lines of differentiated and poorly differentiated types.,similarity:Belongs to the peptidase C2 family.,similarity:Contains 1 calpain catalytic domain.,similarity:Contains 3 EF-hand domains.,tissue specificity:Expressed predominantly in stomach.,
Subcellular Locationintracellular,cytoplasm,
ExpressionBrain,Stomach,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CAPN9. AA range:481-530
Gene NameCAPN9
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Backgroundcalpain 9(CAPN9) Homo sapiens Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-70617-Conjugate. Price: $485 / Size: 100μl.
E20-70617-FITC$485 / 100μlE20-70617-Biotin$485 / 100μlE20-70617-HRP$485 / 100μlE20-70617-AP$485 / 100μlE20-70617-AF350$485 / 100μlE20-70617-AF405M$485 / 100μlE20-70617-AF488$485 / 100μlE20-70617-AF514$485 / 100μlE20-70617-AF532$485 / 100μlE20-70617-AF555$485 / 100μlE20-70617-AF568$485 / 100μlE20-70617-AF405S$485 / 100μlE20-70617-AF405L$485 / 100μlE20-70617-AF546$485 / 100μlE20-70617-AF594$485 / 100μlE20-70617-AF610$485 / 100μlE20-70617-AF635$485 / 100μlE20-70617-AF647$485 / 100μlE20-70617-AF680$485 / 100μlE20-70617-AF700$485 / 100μlE20-70617-AF750$485 / 100μlE20-70617-AF790$485 / 100μlE20-70617-APC$485 / 100μlE20-70617-PE$485 / 100μlE20-70617-Cy3$485 / 100μlE20-70617-Cy5$485 / 100μlE20-70617-Cy5.5$485 / 100μlE20-70617-Cy7$485 / 100μlE20-70617-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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