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Cell Signal Transduction Research Antibodies
Cadherin-8 Polyclonal Antibody
Human;Mouse;Rat
WB;IHC-p;IF/ICC;ELISA
Polyclonal, Rabbit,IgG
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight88253Da
Protein NameCadherin-8
Human Gene Id1006
Human Swiss Prot NoP55286
Mouse Gene Id12564
Mouse Swiss Prot NoP97291
Rat Swiss Prot NoO54800
SpecificityCadherin-8 Polyclonal Antibody detects endogenous levels of Cadherin-8 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCDH8; Cadherin-8
Observed Band(KD)90
Functionfunction:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Mainly expressed in brain. Found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts.,
Subcellular LocationCell membrane; Single-pass type I membrane protein.
ExpressionMainly expressed in brain. Found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CDH8. AA range:491-540
Gene NameCDH8
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundThis gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-70603-Conjugate. Price: $485 / Size: 100μl.
E20-70603-FITC$485 / 100μlE20-70603-Biotin$485 / 100μlE20-70603-HRP$485 / 100μlE20-70603-AP$485 / 100μlE20-70603-AF350$485 / 100μlE20-70603-AF405M$485 / 100μlE20-70603-AF488$485 / 100μlE20-70603-AF514$485 / 100μlE20-70603-AF532$485 / 100μlE20-70603-AF555$485 / 100μlE20-70603-AF568$485 / 100μlE20-70603-AF405S$485 / 100μlE20-70603-AF405L$485 / 100μlE20-70603-AF546$485 / 100μlE20-70603-AF594$485 / 100μlE20-70603-AF610$485 / 100μlE20-70603-AF635$485 / 100μlE20-70603-AF647$485 / 100μlE20-70603-AF680$485 / 100μlE20-70603-AF700$485 / 100μlE20-70603-AF750$485 / 100μlE20-70603-AF790$485 / 100μlE20-70603-APC$485 / 100μlE20-70603-PE$485 / 100μlE20-70603-Cy3$485 / 100μlE20-70603-Cy5$485 / 100μlE20-70603-Cy5.5$485 / 100μlE20-70603-Cy7$485 / 100μlE20-70603-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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